Applications:
✔ Pharmacy Compounding (Chemotherapy/TPN)
✔ Small-Scale Potent Material Handling
✔ Aseptic Processing
✔ Sterility Testing
✔ Research and Development
✔ Cell Processing
Features:
✨ Laminar / Unidirectional airflow that complies to standards for sterile product handling
✨ HEPA (H14) filters with a typical efficiency of > 99.999% at 0.3 microns provide superior ISO Class 5 air cleanliness (Grade A)
✨ Recovery Time to maintain ISO Class 5 environment is less than 60 seconds
✨ Class II Containment as per ISO 10648-2 leak tightness
✨ Type D Passthrough Chambers equipped with electromagnetic interlocking mechanism and time-delay effect
✨ Safe glove change and low contamination filter change
✨ FDA-grade static seals
Principle:
- Ambient air is pulled through the inlet prefilter located on top of the isolator. Air from the top inlet and from work zone is pulled by the fan which creates a positive pressure on the plenum that creates downflow. The HEPA (H14) downflow filter creates a laminar and particle-free ISO Class 5 air cleanliness as per ISO 14644-1 (equivalent to Class 100 as per US Fed Std 209E) inside the isolator to protect the work material inside the main chamber and pass-thru. Air from the work zone and pass-thru is quickly purged out by the fan to keep the area clean. The fan pulls approximately 90% of the purged air back to the plenum and after passing through the HEPA (H14) downflow filter.
- The high rate of airflow recirculation helps to prolong filter life and reduces the chances of ambient contaminants entering the work zone. For a recirculating model, approximately 10% of the purged air is exhausted through an HEPA-filter to prevent heat build-up inside the isolator that can be detrimental to drug compounding. This exhausted air is replenished by ambient air coming from the top inlet prefilter and a filter with 80% efficiency for positive pressure model. For a Total Exhaust/Single-Pass Model, 100% of the air is exhausted out of the isolator.
Some of options for CBI-U:
🔹 BioVap™ sterilization system – utilizes hydrogen peroxide (H₂O₂) gas for decontamination.
🔹 Carbon filter – helps absorb toxic gases during operation.
🔹 Humidity and temperature control system inside the working chamber.
🔹 Integrated weighing device for direct sample weighing in an isolated environment.
🔹 Connection ports for centrifuges, refrigerators, and other equipment.
Specifications:
