One value once shut down an entire production line…
“Why was last week’s WFI batch rejected?” The technical director’s voice echoed during the year-end quality review meeting at a major pharmaceutical manufacturer.
Silence fell across the room.
The QC manager looked down: “TOC exceeded the limit… 0.53 mg/L.”
One number — smaller than a millionth — yet powerful enough to halt the entire production. Not just time lost, it meant discarded product, disrupted delivery timelines, documentation delays, regulatory complications, and perhaps worst of all — damage to brand trust.
TOC – A Critical Indicator You Can’t Afford to Ignore
Total Organic Carbon (TOC) is the definitive indicator of organic contamination in water. It’s not just another number in the report — it’s the last checkpoint before water enters production.
- Pharmaceuticals (WFI, injectable drugs)
- Semiconductors (ultrapure water)
- Food and Beverage
- Industrial wastewater treatment
TOC limits aren’t about best practices — they are regulatory boundaries. Cross them, and your system isn’t out of spec. It’s out of permission to produce.
HORIBA – Two Precision Tools, One Unified Goal: Trusted Water Quality
With over 70 years of experience, HORIBA has long been the name behind precision water analysis. Understanding that no two industries treat water the same, HORIBA developed two specialized TOC analyzers to meet very different but equally critical demands.
HT-110 – Precision TOC Analyzer for Ultrapure Water
A QA engineer in pharmaceutical manufacturing once said: “There’s no room for error. Even a few parts per billion off, and the entire batch is lost.”
HT-110 was made for that exact need: no complexity, no excess, just laser-focused purity control.
Why choose HT-110?
- Ultra-high sensitivity: Detects TOC as low as 0.1 ppb
- Continuous UV oxidation + conductivity detection: No reagents needed
- Fully compliant: USP <643>, EP <2.2.44>, JP <G8.4.5.2>
- 7” touchscreen display, CFR 21 Part 11-compliant security
- Built-in SST (System Suitability Test) for validation and audit readiness
Ideal for: Water for Injection (WFI), purified Water (PW), and ultrapure water in semiconductor manufacturing.
ON-LINE TOC ANALYZER – HT-110 – HORIBA
TOCADERO ONE – The Industrial Warrior for Harsh Water Environments
At a food processing plant, an environmental engineer shared: “Our water was cloudy, salty, greasy. No TOC analyzer lasted more than three weeks…”
TOCADERO ONE was built for exactly such conditions. Where water is dirty. Where operations are nonstop. Where failure is not an option.
Why choose TOCADERO ONE?
- High-temperature combustion at 1200°C – no catalyst required
- Handles extreme samples:
- TOC up to 20,000 mg/L C
- TDS up to 20%, particles up to 2000 microns
- Fast response: 1-minute TC, 3-minute NPOC
- Automatic cleaning, with CBM (Condition-Based Maintenance) for proactive upkeep
- Advanced industrial communication: Profinet, Modbus, OPC UA, Ethernet, Bluetooth, GSM
Ideal for: Industrial wastewater, chemical production, food & beverage, and harsh or complex water matrices
AUTOMATIC TOC ANALYZER – TOCADERO ONE – HORIBA
Quick comparison
| Feature | HT-110 | TOCADERO ONE |
| Method | Continuous UV + Conductivity | 1200°C Combustion (no catalyst) |
| TOC Sensitivity | 0.1 ppb | 0.1 ppm |
| Sample Type | Ultrapure water | Wastewater, brine, complex samples |
| Interface | 7” touchscreen, CFR 21 Part 11 | 7” Touch Panel |
| Self-Cleaning | No | Yes |
Choose the Right TOC Analyzer – Choose Process Safety
“That day, the pharmaceutical plant never failed again. Because they chose the right analyzer. Because they understood: one tiny number can save the entire system.“
Facing a TOC challenge?
Let us help you solve it — with our expertise, technology, and commitment to quality.
Contact us today to receive a consultation, product demo, and a tailored quote for your system.
