Containment Barrier Isolator – III (CBI-III) – ESCO

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Containment Barrier Isolator – Class III Biosafety Cabinet (CBI-III) offers the highest level of operator, product, and environmental protection from infectious/biohazardous aerosols and is suitable for microbiological work with agents assigned to biosafety levels 1,2,3, or 4. It is designed for an absolute level of containment, it is frequently used for work involving the deadliest biohazards, bacteria, viruses, and microorganisms.

CBI-III is configured to operate at a minimum of -125 Pa to provide adequate containment for handling highly pathogenic and lethal biological agents.

Applications:

✔ Laboratory containment for handling biological agents of up to level 4
✔ Virus and vaccine production
✔ Cell Processing
✔ Research and development

Features: 

✨ Fully welded stainless steel 316L internal chambers with stainless steel 304 external housing.
✨ Exhaust air is double-filtered through high-quality ULPA filters (per IEST-RP-CC-001.3) with typical efficiency of >99.999% for 0.1-to-0.3-micron particles, better than HEPA filters.
✨ An integrated pass-through with interlocking doors permits materials transfer without risk of contamination.
✨ Single-piece, leak-tested glove assemblies which guarantee maximum protection.

Principle:

Ambient air enters through the top inlet prefilter and is drawn by a fan, creating positive pressure that pushes clean air downward. A HEPA (H14) filter ensures ISO Class 5 air quality, keeping the main chamber and pass-through contaminant-free.

Around 90% of the air is recirculated, passing through the HEPA filter again, while 10% is exhausted to prevent heat buildup. In a Total Exhaust/Single-Pass Model, all air is expelled, ensuring continuous fresh airflow. This recirculation system extends filter life and reduces contamination risks.

Standard compliance:

• BS EN 12469
• Air Quality: ISO Class 5 (BS EN ISO 14644-1) and EC GMP Grade A
• H14 filters: HEPA as per EN 1822 and ULPA as per IEST-RP-CC001.3

Specifications: 

 

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Containment Barrier Isolator – III (CBI-III) – ESCO

Containment Barrier Isolator - Class III Biosafety Cabinet (CBI-III) offers the highest level of operator, product, and environmental protection from infectious/biohazardous aerosols and is suitable for microbiological work with agents assigned to biosafety levels 1,2,3, or 4. It is designed for an absolute level of containment, it is frequently used for work involving the deadliest biohazards, bacteria, viruses, and microorganisms. CBI-III is configured to operate at a minimum of -125 Pa to provide adequate containment for handling highly pathogenic and lethal biological agents.

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