Water for Injection (WFI) generation systems utilize state-of-the-art technology to deliver water for injections that surpasses global pharmacopoeia standards. The Multi-column Distillation Plant is an exceptionally efficient purification system. With flow rates from 80 liters per hour to 5000 liters per hour, it ensures optimized purity for advanced sterile processes (WFI). This plant features a sleek mechanical design made of SS 316L; all contact parts are electropolished to less than 0.4 RA microns, and the joints are orbitally welded with a video-boroscope. The system is pre-passivated and offers high flexibility with variable production capacities up to 80% without the need for additional plant modifications. Like all TSA technology, it provides quick start-up, enhanced performance, and energy savings, and is compliant with USFDA 21 CFR part 11 and GAMP 5. Options include double tube sheeting, pre-heaters, and exchangers.