OEB5-Level Exposure Control
The system meets OEB5 personnel-protection requirements and has passed third-party testing with an Occupational Exposure Limit (OEL) below 0.05 µg/m³.
A high-pressure exhaust fan generates turbulent airflow and maintains negative pressure inside the working chamber. This operating principle helps contain hazardous powders and compounds, preventing their release into the surrounding environment while reducing the risk of cross-contamination.
An H14 PUSH–PUSH HEPA filtration system supports safe exhaust-air management and facilitates filter replacement under strict containment conditions.
Multiple Processes Integrated into One Closed System
The Tailin Containment Isolator can integrate several processing operations, including:
- Rotary evaporation;
- Filtration;
- Drying;
- Weighing;
- Dispensing;
- Capping.
Combining multiple operations within one enclosed system reduces the need for material transfers, helping minimize operator exposure and cross-contamination while improving process continuity.
A half-suit operating interface can be installed in the rotary evaporation chamber, providing an extended operating radius for equipment handling and complex procedures inside the isolator.
High-Precision Weighing Under Contained Conditions
The system supports weighing accuracy of up to 1/10,000, making it suitable for potent compounds that require precise mass control. Depending on the application, configurations with higher weighing precision and optional vibration-free weighing platforms are also available.
Performing weighing operations directly inside the isolator reduces the number of open handling steps and minimizes the need to move highly potent materials into an uncontrolled environment.
Safe Material Transfer with a Continuous Liner System
Materials are transferred into and out of the isolator through a continuous liner system. This closed transfer method maintains containment during loading and unloading and reduces operator exposure to toxic powders and potent compounds.
All doors are fitted with inflatable seals, while the observation windows are manufactured from 15 mm thick tempered glass. This design provides clear visibility while maintaining the integrity of the contained workspace.
Designed for Processes Involving Volatile Solvents
The isolator incorporates internal explosion-proof protection, making it suitable for processes that may involve volatile or flammable solvents.
For more demanding hazardous environments, an optional fully explosion-proof configuration can be provided to meet EX d IIB T4 and ATEX requirements. The final configuration should be selected according to the process risk assessment and the specific operating environment.
Intuitive Control and a Controlled Processing Environment
The system features a Siemens touchscreen and PLC, enabling operators to monitor and control critical operating parameters through an intuitive interface.
It can be installed in a general background area while maintaining an internal static Grade C environment. This capability helps optimize facility requirements and offers greater flexibility in equipment installation and production-area planning.
Broad Application Coverage
High-Potency Laboratories
Suitable for weighing, dispensing, sampling, solution preparation, analysis, moisture titration, infrared scanning, and other laboratory operations.
Active Pharmaceutical Ingredient Production
Supports centrifugation, filtration, drying, mixing, milling, weighing, dispensing, and related API processes.
Solid Dosage Manufacturing
Applicable to granulation, drying, mixing, tablet compression, coating, and other solid formulation processes.
Beyond ADC synthesis, the isolator is also suitable for HPAPI processing, oncology-drug handling, peptide dissolution, API production, solid dosage manufacturing, laboratory weighing and sampling, and selected sterile pharmaceutical operations.
Technical Specifications
| Fresh Air Supply Volume: ≥600m³/h | Net Weight : 3000kg |
| Public Utilities: Clean compressed air 0.6Mpa＜P＜0.8Mpa | Power: 380V, 16.5kw(Isolator only) |
| Overall Size (mm) : 7122x3377x2985(L*W*H) | Doors: All doors are equipped with inflatable seal, the observation window is made of 15mm thickness tempered glass. |
| It is equipped with an exhaust port on the isolator top, and the piping is connected to the outdoor. |
An Integrated Solution for Highly Potent Compounds
The Tailin Containment Isolator brings together OEB5 containment performance, negative-pressure operation, H14 HEPA filtration, closed material transfer, high-precision weighing, and optional explosion-proof configurations in one integrated platform.
It is an ideal solution for pharmaceutical manufacturers and laboratories seeking to protect their personnel, control cross-contamination, and standardize the handling of ADCs, HPAPIs, and other highly potent or toxic compounds.
